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Chemical Synthesis of GPI Glycan-Peptide Conjugates by Traceless Staudinger Ligation
A new strategy has been developed for GPI glycan-peptide conjugate synthesis based upon a traceless Staudinger reaction between a peptide phosphinothioester and a GPI glycan azide. The strategy was first studied and optimized with simple peptides and GPI glycans, which offered excellent yields of th...
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| Yayımlandı: | Org Lett |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668870/ https://ncbi.nlm.nih.gov/pubmed/28541706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01132 |
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