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Chemical Synthesis of GPI Glycan-Peptide Conjugates by Traceless Staudinger Ligation

A new strategy has been developed for GPI glycan-peptide conjugate synthesis based upon a traceless Staudinger reaction between a peptide phosphinothioester and a GPI glycan azide. The strategy was first studied and optimized with simple peptides and GPI glycans, which offered excellent yields of th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Org Lett
Egile Nagusiak: Zhu, Sanyong, Guo, Zhongwu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668870/
https://ncbi.nlm.nih.gov/pubmed/28541706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01132
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