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Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice

In diabetes mellitus, pituitary adenylate cyclase-activating polypeptide (PACAP) has insulinotropic and glucose-lowering properties. We previously demonstrated that transgenic mice overexpressing PACAP in pancreatic β-cells (PACAP-Tg) show attenuated pancreatic islet hyperplasia and hyperinsulinemia...

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Gepubliceerd in:Biochem Biophys Rep
Hoofdauteurs: Ikeda, Kazuya, Tomimoto, Shuhei, Tsuchiya, Soken, Hamagami, Ken-ichi, Shintani, Norihito, Sugimoto, Yukihiko, Ichikawa, Atsushi, Kasai, Atsushi, Nakazawa, Takanobu, Nagayasu, Kazuki, Hayata-Takano, Atsuko, Baba, Akemichi, Hashimoto, Hitoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668656/
https://ncbi.nlm.nih.gov/pubmed/29124161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.06.006
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