β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking

A pituitary adenylate cyclase-activating polypeptide (PACAP)-specific receptor, PAC1R, is coupled with multiple signal transduction pathways including stimulation of adenylate cyclase, phospholipase C and extracellular-signal regulated kinase (ERK)1/2. PAC1R has been shown to exert its long-lasting...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shintani, Yusuke, Hayata-Takano, Atsuko, Moriguchi, Keita, Nakazawa, Takanobu, Ago, Yukio, Kasai, Atsushi, Seiriki, Kaoru, Shintani, Norihito, Hashimoto, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937772/
https://ncbi.nlm.nih.gov/pubmed/29734363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196946
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