Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells

The regenerating gene, Reg, was originally isolated from a rat regenerating islet cDNA library, and its human homolog was named REG Iα. Recently, we reported that REG Iα mRNA as well as its product were overexpressed in ductal epithelial cells in the minor salivary glands of Sjögren׳s syndrome (SS)...

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Bibliografski detalji
Izdano u:Biochem Biophys Rep
Glavni autori: Fujimura, Takanori, Fujimoto, Takashi, Itaya-Hironaka, Asako, Miyaoka, Tomoko, Yoshimoto, Kiyomi, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Kondo, Saori, Takeda, Maiko, Tsujinaka, Hiroki, Azuma, Masayuki, Tanaka, Yasuhito, Takasawa, Shin
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668644/
https://ncbi.nlm.nih.gov/pubmed/29124146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.05.006
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