Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells

The regenerating gene, Reg, was originally isolated from a rat regenerating islet cDNA library, and its human homolog was named REG Iα. Recently, we reported that REG Iα mRNA as well as its product were overexpressed in ductal epithelial cells in the minor salivary glands of Sjögren׳s syndrome (SS)...

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Pubblicato in:Biochem Biophys Rep
Autori principali: Fujimura, Takanori, Fujimoto, Takashi, Itaya-Hironaka, Asako, Miyaoka, Tomoko, Yoshimoto, Kiyomi, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Kondo, Saori, Takeda, Maiko, Tsujinaka, Hiroki, Azuma, Masayuki, Tanaka, Yasuhito, Takasawa, Shin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668644/
https://ncbi.nlm.nih.gov/pubmed/29124146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.05.006
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