Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells

The regenerating gene, Reg, was originally isolated from a rat regenerating islet cDNA library, and its human homolog was named REG Iα. Recently, we reported that REG Iα mRNA as well as its product were overexpressed in ductal epithelial cells in the minor salivary glands of Sjögren׳s syndrome (SS)...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Fujimura, Takanori, Fujimoto, Takashi, Itaya-Hironaka, Asako, Miyaoka, Tomoko, Yoshimoto, Kiyomi, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Kondo, Saori, Takeda, Maiko, Tsujinaka, Hiroki, Azuma, Masayuki, Tanaka, Yasuhito, Takasawa, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668644/
https://ncbi.nlm.nih.gov/pubmed/29124146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.05.006
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