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Probing the role of aromatic residues in the self-assembly of Aβ(16–22) in fluorinated alcohols and their aqueous mixtures

The Aβ(16–22) sequence KLVFFAE spans the hydrophobic core of the Aβ peptide and plays an important role in its self-assembly. Apart from forming amyloid fibrils, Aβ(16–22) can self-associate into highly ordered nanotubes and ribbon-like structures depending on the composition of solvent used for dis...

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Détails bibliographiques
Publié dans:Biochem Biophys Rep
Auteurs principaux: Pachahara, Sanjai Kumar, Nagaraj, Ramakrishnan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668628/
https://ncbi.nlm.nih.gov/pubmed/29124140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.04.005
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