Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells

AIMS/INTRODUCTION: Overproduction of reactive oxygen species (ROS) in endothelial cells (ECs) plays a pivotal role in endothelial dysfunction. Mitochondrial ROS (mtROS) is one of the key players in the pathogenesis of diabetic vascular complications. Hypoglycemia is linked to increased ROS productio...

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Pubblicato in:J Diabetes Investig
Autori principali: Kajihara, Nobuhiro, Kukidome, Daisuke, Sada, Kiminori, Motoshima, Hiroyuki, Furukawa, Noboru, Matsumura, Takeshi, Nishikawa, Takeshi, Araki, Eiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668512/
https://ncbi.nlm.nih.gov/pubmed/28406580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12678
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