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Acclimatization of the systemic microcirculation to alveolar hypoxia is mediated by an iNOS-dependent increase in nitric oxide availability

Rats breathing 10% O(2) show a rapid and widespread systemic microvascular inflammation that results from nitric oxide (NO) depletion secondary to increased reactive O(2) species (ROS) generation. The inflammation eventually resolves, and the microcirculation becomes resistant to more severe hypoxia...

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Detaylı Bibliyografya
Yayımlandı:J Appl Physiol (1985)
Asıl Yazarlar: Casillan, Alfred J., Chao, Jie, Wood, John G., Gonzalez, Norberto C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668455/
https://ncbi.nlm.nih.gov/pubmed/28302706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00322.2016
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