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Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance

Parkinson disease (PD) is associated with multiple factors, including iron, which is demonstrated to deposit excessively in PD brains. We detected iron deposition by susceptibility weighted image (SWI) and measured the levels of iron metabolism-related proteins and inflammatory factors in cerebrospi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Zhuo, Shen, Hui-cong, Lian, Teng-hong, Mao, Lei, Tang, Shou-xian, Sun, Li, Huang, Xi-yan, Guo, Peng, Cao, Chen-jie, Yu, Shu-yang, Zuo, Li-jun, Wang, Xiao-Min, Chen, Sheng-Di, Chan, Piu, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668412/
https://ncbi.nlm.nih.gov/pubmed/29097764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14721-1
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