Role of influenza A virus NP acetylation on viral growth and replication

Lysine acetylation is a post-translational modification known to regulate protein functions. Here we identify several acetylation sites of the influenza A virus nucleoprotein (NP), including the lysine residues K77, K113 and K229. Viral growth of mutant virus encoding K229R, mimicking a non-acetylat...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Giese, Sebastian, Ciminski, Kevin, Bolte, Hardin, Moreira, Étori Aguiar, Lakdawala, Seema, Hu, Zehan, David, Quinnlan, Kolesnikova, Larissa, Götz, Veronika, Zhao, Yongxu, Dengjel, Jörn, Chin, Y. Eugene, Xu, Ke, Schwemmle, Martin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668263/
https://ncbi.nlm.nih.gov/pubmed/29097654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01112-3
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