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(131)I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment

PURPOSE: Camelid single-domain antibody-fragments (sdAbs) have beneficial pharmacokinetic properties, and those targeted to HER2 can be used for imaging of HER2-overexpressing cancer. Labeled with a therapeutic radionuclide, they may be used for HER2-targeted therapy. Here we describe the generation...

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Publicado en:Clin Cancer Res
Autores principales: D’Huyvetter, Matthias, De Vos, Jens, Xavier, Catarina, Pruszynski, Marek, Sterckx, Yann G. J., Massa, Sam, Raes, Geert, Caveliers, Vicky, Zalutsky, Michael R., Lahoutte, Tony, Devoogdt, Nick
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668161/
https://ncbi.nlm.nih.gov/pubmed/28751451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0310
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