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Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity
Use of some HIV-1 nucleoside reverse transcriptase inhibitors (NRTI) is associated with severe adverse events. However, the exact mechanisms behind their toxicity has not been fully understood. Mitochondrial dysfunction after chronic exposure to specific NRTIs has predominantly been assigned to mito...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5667870/ https://ncbi.nlm.nih.gov/pubmed/29095935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187424 |
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