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H55N polymorphism is associated with low citrate synthase activity which regulates lipid metabolism in mouse muscle cells

The H55N polymorphism in the Cs gene of A/J mice has been linked to low activity of the enzyme in skeletal muscles. The aim of the study was to test this hypothesis and examine effects of low citrate synthase (CS) activity on palmitate metabolism in muscle cells. Results of the study showed that car...

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Bibliographic Details
Published in:PLoS One
Main Authors: Gabriel, Brendan M., Al-Tarrah, Mustafa, Alhindi, Yosra, Kilikevicius, Audrius, Venckunas, Tomas, Gray, Stuart R., Lionikas, Arimantas, Ratkevicius, Aivaras
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667803/
https://ncbi.nlm.nih.gov/pubmed/29095821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185789
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