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Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors
Src-family kinases (SFKs) play important roles in human biology and are key drug targets as well. However, achieving selective inhibition of individual Src-family kinases is challenging due to the high similarity within the protein family. We describe rhodium(ii) conjugates that deliver both potent...
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| Foilsithe in: | Chem Sci |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Royal Society of Chemistry
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5667506/ https://ncbi.nlm.nih.gov/pubmed/29142714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01602a |
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