High Endogenous Accumulation of ω-3 Polyunsaturated Fatty Acids Protect against Ischemia-Reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice

Regulated autophagy is involved in the repair of renal ischemia-reperfusion injury (IRI). Fat-1 transgenic mice produce ω3-Polyunsaturated fatty acids (ω3-PUFAs) from ω6-Polyunsaturated fatty acids (ω6-PUFAs) without a dietary ω3-PUFAs supplement, leading to a high accumulation of omega-3 in various...

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Pubblicato in:Int J Mol Sci
Autori principali: Gwon, Do Hyeong, Hwang, Tae Woong, Ro, Ju-Ye, Kang, Yoon-Joong, Jeong, Jin Young, Kim, Do-Kyung, Lim, Kyu, Kim, Dong Woon, Choi, Dae Eun, Kim, Jwa-Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666763/
https://ncbi.nlm.nih.gov/pubmed/28974016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102081
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