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High Endogenous Accumulation of ω-3 Polyunsaturated Fatty Acids Protect against Ischemia-Reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice
Regulated autophagy is involved in the repair of renal ischemia-reperfusion injury (IRI). Fat-1 transgenic mice produce ω3-Polyunsaturated fatty acids (ω3-PUFAs) from ω6-Polyunsaturated fatty acids (ω6-PUFAs) without a dietary ω3-PUFAs supplement, leading to a high accumulation of omega-3 in various...
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出版年: | Int J Mol Sci |
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主要な著者: | , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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MDPI
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666763/ https://ncbi.nlm.nih.gov/pubmed/28974016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102081 |
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