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Molecular Imaging of P-glycoprotein in Chemoresistant Tumors using a Dual-Modality PET/Fluorescence Probe

Overexpression of P-glycoprotein (Pgp) has been considered a primary cause for multidrug resistance in a variety of cancers for three decades. However, clinical translation of Pgp targeted therapeutics has been hindered by lack of patient preselection based on the Pgp presence in tumors. We aim to d...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Wang, Mengzhe, Mao, Chengqiong, Wang, Hui, Ling, Xueying, Wu, Zhanhong, Li, Zibo, Ming, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666568/
https://ncbi.nlm.nih.gov/pubmed/28813596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00420
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