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Synthesis and Evaluation of (64)Cu-DOTA-NT-Cy5.5 as a Dual-Modality PET/Fluorescence Probe to Image Neurotensin Receptor-Positive Tumor

Overexpression of neurotensin receptors (NTRs) has been suggested to play important roles in the growth and survival of a variety of tumor types. The aim of this study is to develop a dual-modality probe ((64)Cu -DOTA-NT-Cy5.5) for imaging NTR1 expression in vivo with both positron emission tomograp...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Deng, Huaifu, Wang, Hui, Wang, Mengzhe, Li, Zibo, Wu, Zhanhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460915/
https://ncbi.nlm.nih.gov/pubmed/26162008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00325
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