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Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with cyclase, pore-forming, and hemolytic activities. Pos...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Bouchez, Valérie, Douché, Thibaut, Dazas, Mélody, Delaplane, Sophie, Matondo, Mariette, Chamot-Rooke, Julia, Guiso, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666351/
https://ncbi.nlm.nih.gov/pubmed/28954396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9100304
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