The C-terminal domain is essential for protective activity of the Bordetella pertussis adenylate cyclase-hemolysin.
The adenylate cyclase-hemolysin of Bordetella pertussis consists of a cell-invasive N-terminal adenylate cyclase domain linked to a C-terminal RTX hemolysin containing extensive glycine-rich repeats. The toxin is an essential virulence factor required in the initial stages of infection. Adenylate cy...
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| Udgivet i: | Infect Immun |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7642260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.9.3309-3315.1995 |
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