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Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice

The aim of this study was to determine whether low dose doxycycline as an anti-inflammatory agent could improve glucose metabolism in diabetic animals. Therefore, doxycycline was supplemented in drinking water to 6-week-old male db/db mice for 10 weeks. Doxycycline reduced perirenal/epididymal fat,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Na, Tian, Xiong, Chen, Yu, Tan, Hui-qi, Xie, Pei-jian, Chen, Shao-jun, Fu, Yu-cai, Chen, Yi-xin, Xu, Wen-can, Wei, Chi-ju
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666019/
https://ncbi.nlm.nih.gov/pubmed/29089617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14408-7
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