Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia

Exosomes, small (30–150 nm) extracellular vesicles (EVs) isolated from plasma of patients with acute myeloid leukemia (AML) carry leukemia-associated antigens and multiple inhibitory molecules. Circulating exosomes can deliver suppressive cargos to immune recipient cells, inhibiting anti-tumor activ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Hong, Chang-Sook, Sharma, Priyanka, Yerneni, Saigopalakrishna S., Simms, Patricia, Jackson, Edwin K., Whiteside, Theresa L., Boyiadzis, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666018/
https://ncbi.nlm.nih.gov/pubmed/29089618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14661-w
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