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Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2′3′-cAMP

Exosome secretion by cells is a complex, poorly understood process. Studies of exosomes would be facilitated by a method for increasing their production and release. Here, we present a method for stimulating the secretion of exosomes. Cultured cells were treated or not with sodium iodoacetate (IAA;...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ludwig, Nils, Yerneni, Saigopalakrishna S., Menshikova, Elizabeth V., Gillespie, Delbert G., Jackson, Edwin K., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181876/
https://ncbi.nlm.nih.gov/pubmed/32332778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63658-5
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