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Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate

Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool. Here we use quantitative analysis of Wnt, Hh, and Notch signalling reporters and...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Dai, Wei, Peterson, Amy, Kenney, Thomas, Burrous, Haley, Montell, Denise J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665863/
https://ncbi.nlm.nih.gov/pubmed/29093440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01322-9
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