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Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery

A casposon, a member of a distinct superfamily of archaeal and bacterial self-synthesizing transposons that employ a recombinase (casposase) homologous to the Cas1 endonuclease, appears to have given rise to the adaptation module of CRISPR-Cas systems as well as the CRISPR repeats themselves. Compar...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Microbiol
Hauptverfasser: Krupovic, Mart, Béguin, Pierre, Koonin, Eugene V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665730/
https://ncbi.nlm.nih.gov/pubmed/28472712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2017.04.004
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