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Dimethyl fumarate induces changes in B- and T-lymphocyte function independent of effects on absolute lymphocyte count

BACKGROUND: Dimethyl fumarate (DMF) is used to treat relapsing multiple sclerosis and causes lymphopenia in a subpopulation of treated individuals. Much remains to be learned about how the drug affects B- and T-lymphocytes. OBJECTIVES: To characterize changes in B- and T-cell phenotype and function...

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Detalhes bibliográficos
Publicado no:Mult Scler
Main Authors: Longbrake, Erin E., Cantoni, Claudia, Chahin, Salim, Cignarella, Francesca, Cross, Anne H., Piccio, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665729/
https://ncbi.nlm.nih.gov/pubmed/28480794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458517707069
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