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Dimethyl fumarate induces changes in B- and T-lymphocyte function independent of effects on absolute lymphocyte count

BACKGROUND: Dimethyl fumarate (DMF) is used to treat relapsing multiple sclerosis and causes lymphopenia in a subpopulation of treated individuals. Much remains to be learned about how the drug affects B- and T-lymphocytes. OBJECTIVES: To characterize changes in B- and T-cell phenotype and function...

詳細記述

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書誌詳細
出版年:Mult Scler
主要な著者: Longbrake, Erin E., Cantoni, Claudia, Chahin, Salim, Cignarella, Francesca, Cross, Anne H., Piccio, Laura
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665729/
https://ncbi.nlm.nih.gov/pubmed/28480794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458517707069
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