Načítá se...
CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape
CRISPRi, an adapted CRISPR-Cas9 system, is proposed to act as a strand-specific roadblock to repress transcription in eukaryotic cells using guide RNAs (sgRNAs) to target catalytically inactive Cas9 (dCas9) and offers an alternative to genetic interventions for studying pervasive antisense transcrip...
Uloženo v:
| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665645/ https://ncbi.nlm.nih.gov/pubmed/29058669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29878 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|