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The cathelicidin protein CRAMP is a potential atherosclerosis self-antigen in ApoE(-/-) mice

Auto-immunity is believed to contribute to inflammation in atherosclerosis. The antimicrobial peptide LL-37, a fragment of the cathelicidin protein precursor hCAP18, was previously identified as an autoantigen in psoriasis. Given the reported link between psoriasis and coronary artery disease, the b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mihailovic, Peter M., Lio, Wai Man, Yano, Juliana, Zhao, Xiaoning, Zhou, Jianchang, Chyu, Kuang-Yuh, Shah, Prediman K., Cercek, Bojan, Dimayuga, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665601/
https://ncbi.nlm.nih.gov/pubmed/29091929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187432
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