Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice

Recent studies suggest the potential involvement of CD8+ T cells in the pathogenesis of murine hypertension. We recently reported that immunization with apoB-100 related peptide, p210, modified CD8+ T cell function in angiotensin II (AngII)-infused apoE (-/-) mice. In this study, we hypothesized tha...

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Publicado en:PLoS One
Main Authors: Honjo, Tomoyuki, Chyu, Kuang-Yuh, Dimayuga, Paul C., Lio, Wai Man, Yano, Juliana, Trinidad, Portia, Zhao, Xiaoning, Zhou, Jianchang, Cercek, Bojan, Shah, Prediman K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486456/
https://ncbi.nlm.nih.gov/pubmed/26121471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131731
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