Ig-like transcript 2 (ILT2) suppresses T cell function in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is associated with a profound dysregulation of the immune system. Loss of T cell function is frequently caused in cancer by sustained signaling of inhibitory receptors. Here, we analyzed the role of the novel inhibitory receptor Ig-like transcript 2 (ILT2) in the p...

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Udgivet i:Oncoimmunology
Main Authors: Villa-Álvarez, Mónica, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., López-Soto, Alejandro, Payer, Angel R., Gonzalez-Garcia, Esther, Huergo-Zapico, Leticia, Gonzalez, Segundo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665082/
https://ncbi.nlm.nih.gov/pubmed/29123965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1353856
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