Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma

Merkel cell carcinoma (MCC) is a rare skin cancer caused by Merkel cell polyomavirus (MCPyV) infection and/or ultraviolet radiation–induced somatic mutations. The presence of tumor-infiltrating lymphocytes is evidence that an active immune response to MCPyV and tumor-associated neoantigens occurs in...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Schadendorf, Dirk, Nghiem, Paul, Bhatia, Shailender, Hauschild, Axel, Saiag, Philippe, Mahnke, Lisa, Hariharan, Subramanian, Kaufman, Howard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665072/
https://ncbi.nlm.nih.gov/pubmed/29123950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338237
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