Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

The universal modular chimeric antigen receptor (UniCAR) platform redirects CAR-T cells using a separated, soluble targeting module with a short half-life. This segregation allows precise controllability and flexibility. Herein we show that the UniCAR platform can be used to efficiently target solid...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Pishali Bejestani, Elham, Cartellieri, Marc, Bergmann, Ralf, Ehninger, Armin, Loff, Simon, Kramer, Michael, Spehr, Johannes, Dietrich, Antje, Feldmann, Anja, Albert, Susann, Wermke, Martin, Baumann, Michael, Krause, Mechthild, Bornhäuser, Martin, Ehninger, Gerhard, Bachmann, Michael, von Bonin, Malte
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665068/
https://ncbi.nlm.nih.gov/pubmed/29123951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1342909
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