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Arecoline Increases Glycolysis and Modulates pH Regulator Expression in HA22T/VGH Hepatoma Cells, Leading to Increase of Intracellular Ca(2+), Reactive Oxygen Species, and Anoikis

Background: Cancer cells proliferate rapidly and are resistant to cell death, relying on aggravated glycolysis to satisfy their increased demand for energy and biosynthetic precursors. However, this process may create unfavorable microenvironments, such as increased acidity, leading to cytotoxicity....

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Cheng, Hsiao-Ling, Chang, Wen-Tsan, Hu, Yu-Chen, Hsieh, Bau-Shan, Huang, Tzu-Ching, Chong, Inn-Wen, Huang, Li-Wen, Chang, Kee-Lung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665033/
https://ncbi.nlm.nih.gov/pubmed/29158789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20523
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