Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation

BACKGROUND: Our previous study showed that, in basal cell carcinoma cells, arecoline reduces levels of the tumor cell survival factor interleukin-6 (IL-6), increases levels of tumor suppressor factor p53, and elicits cell cycle arrest, followed by apoptosis. In preliminarily studies, we observed tha...

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Bibliografiske detaljer
Main Authors: Cheng, Hsiao-Ling, Su, Shu-Jem, Huang, Li-Wen, Hsieh, Bau-Shan, Hu, Yu-Chen, Hung, Thu-Ching, Chang, Kee-Lung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895595/
https://ncbi.nlm.nih.gov/pubmed/20507639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-126
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