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Paroxysmal nocturnal haemoglobinuria treatment with eculizumab is associated with a positive direct antiglobulin test

BACKGROUND/OBJECTIVES: Paroxysmal nocturnal haemoglobinuria (PNH) is characterized by intravascular haemolysis with a negative direct antiglobulin test (DAT). Eculizumab is a humanized monoclonal antibody that inhibits complement component C5 and is approved for PNH treatment. Recent publications de...

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Bibliografski detalji
Izdano u:Vox Sang
Glavni autori: Höchsmann, B., Leichtle, R., von Zabern, I., Kaiser, S., Flegel, W. A., Schrezenmeier, H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664937/
https://ncbi.nlm.nih.gov/pubmed/21929681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1423-0410.2011.01530.x
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