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Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo
Oligodendrocytes in the central nervous system produce myelin, a lipid-rich, multilamellar sheath that surrounds axons and promotes the rapid propagation of action potentials. A critical component of myelin is myelin basic protein (MBP), expression of which requires anterograde mRNA transport follow...
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Publié dans: | Proc Natl Acad Sci U S A |
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Auteurs principaux: | , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5664533/ https://ncbi.nlm.nih.gov/pubmed/29073112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711088114 |
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