Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

Oligodendrocytes in the central nervous system produce myelin, a lipid-rich, multilamellar sheath that surrounds axons and promotes the rapid propagation of action potentials. A critical component of myelin is myelin basic protein (MBP), expression of which requires anterograde mRNA transport follow...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Herbert, Amy L., Fu, Meng-meng, Drerup, Catherine M., Gray, Ryan S., Harty, Breanne L., Ackerman, Sarah D., O’Reilly-Pol, Thomas, Johnson, Stephen L., Nechiporuk, Alex V., Barres, Ben A., Monk, Kelly R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664533/
https://ncbi.nlm.nih.gov/pubmed/29073112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711088114
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