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Signal transduction and amplification through enzyme-triggered ligand release and accelerated catalysis

Signal transduction and signal amplification are both important mechanisms used within biological signalling pathways. Inspired by this process, we have developed a signal amplification methodology that utilises the selectivity and high activity of enzymes in combination with the robustness and gene...

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Detalles Bibliográficos
Publicado en:Chem Sci
Main Authors: Goggins, Sean, Marsh, Barrie J., Lubben, Anneke T., Frost, Christopher G.
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664363/
https://ncbi.nlm.nih.gov/pubmed/29142726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01588j
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