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A Reevaluation of the Origin of the Rate Acceleration for Enzyme-Catalyzed Hydride Transfer

There is no consensus of opinion on the origin of the large rate accelerations observed for enzyme-catalyzed hydride transfer. The interpretation of recent results from studies on hydride transfer reactions catalyzed by alcohol dehydrogenase (ADH) focus on the proposal that the effective barrier hei...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Reyes, Archie C., Amyes, Tina L., Richard, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664202/
https://ncbi.nlm.nih.gov/pubmed/28956050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob01652b
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