Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

Basal Cell Carcinoma (BCC) is one of the most diagnosed cancers worldwide. It develops due to an unrestrained Sonic Hedgehog (SHH) signaling activity in basal cells of the skin. Certain subtypes of BCC are more aggressive than others, although the molecular basis of this phenomenon remains unknown....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Casas, Bárbara S., Adolphe, Christelle, Lois, Pablo, Navarrete, Nelson, Solís, Natalia, Bustamante, Eva, Gac, Patricio, Cabané, Patricio, Gallegos, Ivan, Wainwright, Brandon J., Palma, Verónica
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663572/
https://ncbi.nlm.nih.gov/pubmed/29137400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21061
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