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Neogenin regulates Sonic hedgehog pathway activity during digit patterning
BACKGROUND: Digit patterning integrates signaling by the Sonic Hedgehog (SHH), FGF and BMP pathways. GLI3, a component of the SHH pathway, is a major regulator of digit number and identity. Neogenin (encoded by Neo1) is a cell surface protein that serves to transduce signals from several ligands, in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424067/ https://ncbi.nlm.nih.gov/pubmed/22275192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23745 |
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