Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of conventional RNA-sequencing methods. Here we present...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shurtleff, Matthew J., Yao, Jun, Qin, Yidan, Nottingham, Ryan M., Temoche-Diaz, Morayma M., Schekman, Randy, Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663387/
https://ncbi.nlm.nih.gov/pubmed/29073095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712108114
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