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Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

Exosomes are small vesicles that are secreted from metazoan cells and may convey selected membrane proteins and small RNAs to target cells for the control of cell migration, development and metastasis. To study the mechanisms of RNA packaging into exosomes, we devised a purification scheme based on...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Shurtleff, Matthew J, Temoche-Diaz, Morayma M, Karfilis, Kate V, Ri, Sayaka, Schekman, Randy
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047747/
https://ncbi.nlm.nih.gov/pubmed/27559612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19276
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