Neural precursor cell–secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity

In multiple sclerosis, the pathological interaction between autoreactive Th cells and mononuclear phagocytes in the CNS drives initiation and maintenance of chronic neuroinflammation. Here, we found that intrathecal transplantation of neural stem/precursor cells (NPCs) in mice with experimental auto...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: De Feo, Donatella, Merlini, Arianna, Brambilla, Elena, Ottoboni, Linda, Laterza, Cecilia, Menon, Ramesh, Srinivasan, Sundararajan, Farina, Cinthia, Garcia Manteiga, Jose Manuel, Butti, Erica, Bacigaluppi, Marco, Comi, Giancarlo, Greter, Melanie, Martino, Gianvito
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663358/
https://ncbi.nlm.nih.gov/pubmed/28945200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92387
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires