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Endothelial transplantation rejuvenates aged hematopoietic stem cell function

Age-related changes in the hematopoietic compartment are primarily attributed to cell-intrinsic alterations in hematopoietic stem cells (HSCs); however, the contribution of the aged microenvironment has not been adequately evaluated. Understanding the role of the bone marrow (BM) microenvironment in...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Poulos, Michael G., Ramalingam, Pradeep, Gutkin, Michael C., Llanos, Pierre, Gilleran, Katherine, Rabbany, Sina Y., Butler, Jason M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663355/
https://ncbi.nlm.nih.gov/pubmed/29035282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93940
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