Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand

OBJECTIVE: We previously reported that the olfactory receptor OR51E2, overexpressed in LNCaP prostate cancer cells, promotes cell invasiveness upon stimulation of its agonist β-ionone, and this phenomenon increases metastatic spread. Furthermore, we showed that the induced cell invasiveness involves...

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Bibliografski detalji
Izdano u:BMC Res Notes
Glavni autori: Sanz, Guenhaël, Leray, Isabelle, Muscat, Adeline, Acquistapace, Adrien, Cui, Tao, Rivière, Julie, Vincent-Naulleau, Silvia, Giandomenico, Valeria, Mir, Lluis M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Note
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663063/
https://ncbi.nlm.nih.gov/pubmed/29084601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2879-z
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