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Silencing of odorant receptor gene expression by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron

Olfactory sensory neurons express just one out of a possible ~1000 odorant receptor genes, reflecting an exquisite mode of gene regulation. In one model, once an odorant receptor is chosen for expression, other receptor genes are suppressed by a negative feedback mechanism, ensuring a stable functio...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Ferreira, Todd, Wilson, Sarah R., Choi, Yoon Gi, Risso, Davide, Dudoit, Sandrine, Speed, Terence P., Ngai, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412037/
https://ncbi.nlm.nih.gov/pubmed/24559675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.001
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