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Poly r(C) binding protein (PCBP) 1 expression is regulated by the E3 ligase UBE4A in thyroid carcinoma

Thyroid cancer patients with high miR-490-3p inhibit translation of PCBP1 mRNA, whereas in patients with low miR-490-3p PCBP1 mRNA expression is high; however, the resultant protein is targeted for degradation through the proteasome. The objective of the present study was to evaluate the molecular m...

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Библиографические подробности
Опубликовано в: :Biosci Rep
Главные авторы: Zhang, Ming-Peng, Zhang, Wei-San, Tan, Jin, Zhao, Ming-Hui, Lian, Lin-Juan, Cai, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662924/
https://ncbi.nlm.nih.gov/pubmed/28963376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170114
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